Opportunity Information: Apply for CDC RFA GH19 1947

The Initiative for TB/HIV Program Collaboration and Service Integration in the Central America Region is a PEPFAR-supported CDC funding opportunity designed to reduce illness and deaths from TB among people living with HIV by improving how TB and HIV services work together across Central America. The rationale is straightforward and urgent: tuberculosis is responsible for roughly one third of HIV-related deaths worldwide, and the most effective way to bring that number down is to combine antiretroviral therapy with core TB/HIV collaborative activities such as routine TB screening for people living with HIV, timely provision of TB preventive therapy, and strong TB infection control practices in health care settings. In the Central America context described in the opportunity, TB and HIV programs are often run in parallel rather than as a coordinated package, leaving major gaps in patient-centered care and missed chances to prevent TB, diagnose it earlier, and treat it effectively.

The opportunity focuses on fixing several practical barriers that have been limiting progress in the region. A key problem identified is weak integration between national TB and HIV programs, which can result in fragmented services, inconsistent clinical practices, and unclear referral pathways. Another major issue is data quality: TB/HIV registries are described as incomplete and inaccurate, which undermines surveillance, planning, and accountability, and makes it harder for Ministries of Health to know where the biggest gaps are or whether interventions are working. The notice also points to workforce limitations, noting that many health care workers have limited experience with TB/HIV care and treatment, a challenge that can lead to delayed diagnoses, inconsistent preventive therapy use, and uneven quality of clinical management.

To address these challenges, the initiative is structured around technical assistance and capacity building in partnership with national governments and major global and regional health actors. The CDC expects the implementing partner to work closely with Ministries of Health to support true service integration, meaning TB and HIV activities are aligned in guidelines, workflows, and delivery sites rather than treated as separate programs. The work also includes helping countries develop, review, and disseminate national TB/HIV guidelines and to support law or policy initiatives that strengthen TB/HIV collaboration. This policy and guideline component is meant to institutionalize best practices so improvements persist beyond individual projects and are applied consistently across facilities and jurisdictions.

A central implementation component is the expansion of the TB ECHO Project, which uses the Project ECHO model (hub-and-spoke tele-mentoring) to build frontline clinical and public health capacity through case-based learning and regular virtual sessions. In practical terms, this means creating sustained learning networks where experienced specialists mentor providers in real-world TB/HIV case management, improving confidence and competence in diagnosing TB in people with HIV, initiating and monitoring TB preventive therapy, managing co-treatment, handling drug interactions and adherence challenges, and applying infection control measures. This approach is designed to reach many providers efficiently, including those in underserved or remote settings, and to standardize decision-making through continuous mentoring rather than one-time trainings.

The initiative also places heavy emphasis on strengthening information systems to improve TB/HIV data management and analysis. The aim is to improve the completeness, accuracy, and usefulness of registries and reporting systems so that programs can track key indicators, identify service gaps, and make timely corrections. Better data systems also support stronger surveillance and monitoring and evaluation, allowing countries and partners to measure integration progress, assess outcomes like screening coverage or preventive therapy uptake, and evaluate impacts on TB incidence and mortality among people living with HIV.

Operationally, this is a CDC discretionary cooperative agreement, which usually means substantial involvement by CDC in technical direction and collaboration rather than a hands-off grant. The funding opportunity number is CDC RFA GH19-1947 under CFDA 93.067, administered by the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CGH). Eligibility is listed as unrestricted, meaning a wide range of entities may apply as long as they meet any requirements described in the full announcement. The expected number of awards is one, indicating CDC anticipated selecting a single implementing partner to lead the regional effort. The award ceiling is $1,500,000. The opportunity was created on August 3, 2018, with an original application deadline of October 2, 2018 (electronic submissions due by 11:59 p.m. ET).

Finally, the initiative is designed to be collaborative at both the country and regional levels, explicitly aligning with and leveraging the roles of partners such as the Global Fund, PAHO, USAID, The Union, COMISCA, and the TB Parliamentary Group. The technical group supporting the work is expected to include experts from Ministries of Health, CDC, and the implementing partner across TB/HIV clinical and program areas, data management, surveillance, information systems, and monitoring and evaluation. Taken together, the grant aims to move Central American TB/HIV efforts from fragmented services and weak data toward coordinated, guideline-driven care supported by a better-trained workforce and stronger information systems.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Initiative for TB/HIV Program Collaboration and Service Integration in the Central America Region under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Aug 03, 2018.
  • Applicants must submit their applications by Oct 02, 2018 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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