Opportunity Information: Apply for CDC RFA DP22 2207

The Statewide Perinatal Quality Collaboratives (PQCs) funding opportunity (CDC RFA DP22-2207) is a CDC cooperative agreement designed to strengthen and expand statewide efforts to improve maternal and infant health outcomes through structured quality improvement (QI) work. PQCs are described as established, multidisciplinary networks that bring together clinicians, hospitals, health systems, public health partners, and other stakeholders to implement evidence-based practices and make measurable, population-level improvements in perinatal care across an entire state or multi-state region. A core expectation is that PQCs do more than run isolated projects; they help healthcare facilities learn from each other, provide hands-on technical assistance for QI implementation, and then spread successful interventions, policy changes, and care practice improvements statewide.

A central theme of this notice of funding opportunity is building capacity so PQCs can move faster and achieve clearer, measurable results, while also ensuring that the benefits of improved care reach all communities fairly. The NOFO explicitly emphasizes equity, meaning applicants and awardees are expected to incorporate a health equity lens into QI initiatives so that improvements are not limited to certain hospitals, regions, or patient groups. In practice, that focus implies attention to disparities in perinatal outcomes and support for strategies that help close gaps tied to geography, race and ethnicity, socioeconomic status, and other factors that influence access and quality of care.

The opportunity is organized into two components. Component A focuses on strengthening individual state or multi-state PQCs so they can rapidly design and execute population-level perinatal QI initiatives, support participating facilities, and demonstrate measurable improvements. Component A also places particular weight on equitable distribution of benefits, reinforcing the expectation that QI activities should be implemented and evaluated in ways that reach high-need settings and populations and that improvements can be demonstrated across different groups rather than averaging out gains that may mask persistent inequities.

Component B is more national in scope and is meant to support the broader infrastructure that helps PQCs succeed everywhere, not just in one state. Under Component B, the recipient provides technical assistance, training, and capacity-building support to PQCs across the United States to increase the overall uptake and effectiveness of perinatal QI initiatives nationwide. This component also includes a strong equity integration role: the Component B awardee is expected to work with interested PQCs to embed a health equity perspective into QI design, implementation, measurement, and dissemination, with the goal of improving perinatal outcomes while also making sure gains are shared equitably.

From an administrative standpoint, the program is offered by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC), within NCCDPHP, and it is categorized as a discretionary cooperative agreement (meaning CDC is expected to have substantial involvement, often through collaboration, guidance, and coordinated support rather than acting solely as a pass-through funder). The CFDA number listed is 93.946. The award ceiling is $750,000, and CDC anticipated making 23 awards under this announcement. The original posting shows a creation date of April 6, 2022 and an original application deadline of June 6, 2022, with electronic submissions due by 11:59 pm ET on the due date.

Eligibility is broad and includes many types of entities that could lead or support statewide perinatal improvement work, such as state, county, city, and special district governments; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses); and other entities as allowed by the additional eligibility language. Overall, the NOFO is aimed at building durable statewide and national capability to run effective perinatal QI collaboratives, spread proven clinical and system changes, and improve maternal and infant outcomes with an explicit requirement to address equity so that improvements reach all populations.

  • The Department of Health and Human Services, Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "Statewide Perinatal Quality Collaboratives" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.946.
  • This funding opportunity was created on Apr 06, 2022.
  • Applicants must submit their applications by Jun 06, 2022 Electronically submitted applications must be submitted no later than 1159 pm ET on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $750,000.00 in funding.
  • The number of recipients for this funding is limited to 23 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA DP22 2207

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Frequently Asked Questions (FAQs): Statewide Perinatal Quality Collaboratives (PQCs) Funding Opportunity (CDC RFA DP22-2207)

1) What is the Statewide Perinatal Quality Collaboratives (PQCs) funding opportunity (CDC RFA DP22-2207)?

This opportunity is a CDC cooperative agreement designed to strengthen and expand statewide efforts to improve maternal and infant health outcomes through structured quality improvement (QI) work. It supports Perinatal Quality Collaboratives (PQCs), which are established, multidisciplinary networks that implement evidence-based practices and aim for measurable, population-level improvements in perinatal care across an entire state or multi-state region.

2) What is a Perinatal Quality Collaborative (PQC) in the context of this program?

PQCs are described as established, multidisciplinary networks that bring together clinicians, hospitals, health systems, public health partners, and other stakeholders. Their role is to implement evidence-based practices, provide hands-on support to participating facilities, and drive measurable improvements in perinatal care at a population level across a whole state or multi-state region.

3) What is the main purpose of this funding opportunity?

The main purpose is to build capacity so PQCs can move faster and achieve clearer, measurable results in improving maternal and infant health outcomes. The program also emphasizes ensuring that improvements in care reach all communities fairly, with explicit expectations around incorporating equity into QI initiatives.

4) What does the CDC mean by "structured quality improvement (QI) work" for PQCs?

Within this opportunity, structured QI work refers to organized, evidence-based efforts where PQCs help facilities learn from each other, provide hands-on technical assistance for implementation, and spread successful interventions, policy changes, and care practice improvements across a state or region. The expectation is not isolated projects, but coordinated work that leads to measurable, population-level change.

5) Is the program focused on single projects, or on broader statewide change?

The program explicitly expects PQCs to do more than run isolated projects. A core expectation is that PQCs will support cross-facility learning, provide implementation support, and then spread successful interventions and practice improvements statewide (or across a multi-state region), achieving measurable population-level improvements.

6) How does health equity factor into this funding opportunity?

Equity is a central theme of the notice of funding opportunity (NOFO). Applicants and awardees are expected to incorporate a health equity lens into QI initiatives so improvements are not limited to certain hospitals, regions, or patient groups. The NOFO implies attention to disparities in perinatal outcomes and strategies to help close gaps tied to geography, race and ethnicity, socioeconomic status, and other factors influencing access and quality of care.

7) What does "equitable distribution of benefits" mean for Component A activities?

Component A places particular weight on ensuring that QI activities are implemented and evaluated in ways that reach high-need settings and populations. It also emphasizes demonstrating improvements across different groups, rather than relying on overall averages that could hide persistent inequities.

8) How is this opportunity organized?

The opportunity is organized into two components: Component A, focused on strengthening individual state or multi-state PQCs; and Component B, focused on providing national technical assistance, training, and capacity-building support to PQCs across the United States.

9) What is Component A?

Component A focuses on strengthening individual state or multi-state PQCs so they can rapidly design and execute population-level perinatal QI initiatives, support participating facilities, and demonstrate measurable improvements. It reinforces the expectation that QI benefits should be distributed equitably and demonstrated across different populations and settings.

10) What is Component B?

Component B is national in scope and supports the broader infrastructure that helps PQCs succeed across the United States. Under Component B, the recipient provides technical assistance, training, and capacity-building support to PQCs nationwide to increase the uptake and effectiveness of perinatal QI initiatives. It also includes an equity integration role to help PQCs embed a health equity perspective into QI design, implementation, measurement, and dissemination.

11) Who administers this program?

The program is offered by the Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), within NCCDPHP.

12) What type of award is this?

This is a discretionary cooperative agreement. That means CDC is expected to have substantial involvement, often through collaboration, guidance, and coordinated support, rather than acting only as a pass-through funder.

13) What is the CFDA number for this opportunity?

The CFDA number listed is 93.946.

14) What is the maximum award amount (award ceiling)?

The award ceiling listed is $750,000.

15) How many awards did CDC anticipate making under this announcement?

CDC anticipated making 23 awards under this announcement.

16) What were the key dates for the original posting and deadline?

The original posting shows a creation date of April 6, 2022 and an original application deadline of June 6, 2022.

17) What time were electronic submissions due?

Electronic submissions were due by 11:59 pm ET on the due date.

18) Who is eligible to apply?

Eligibility is broad and includes: state, county, city, and special district governments; public and private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with or without 501(c)(3) status; for-profit organizations (including small businesses); and other entities as allowed by the additional eligibility language.

19) Are for-profit organizations eligible?

Yes. The eligibility list includes for-profit organizations, including small businesses.

20) Are tribal governments and tribal organizations eligible?

Yes. The eligibility list includes federally recognized tribal governments and other tribal organizations.

21) Are institutions of higher education eligible?

Yes. Both public and private institutions of higher education are included in the eligibility description.

22) Are nonprofit organizations required to have 501(c)(3) status to be eligible?

No. The eligibility description includes nonprofit organizations with or without 501(c)(3) status.

23) What kinds of partners are PQCs expected to involve?

PQCs are described as multidisciplinary networks that bring together clinicians, hospitals, health systems, public health partners, and other stakeholders to support evidence-based perinatal care improvements.

24) What outcomes is the program trying to improve?

The program is focused on improving maternal and infant health outcomes through measurable, population-level improvements in perinatal care.

25) What does "population-level" improvement imply in this NOFO?

It implies changes that can be measured across an entire state or multi-state region, not just within one facility. The PQC model is expected to support multiple facilities, spread successful interventions and practice changes, and show measurable improvements across broad populations.

26) What kinds of activities are PQCs expected to do beyond implementing evidence-based practices?

Beyond implementing evidence-based practices, PQCs are expected to help healthcare facilities learn from each other, provide hands-on technical assistance for QI implementation, and spread successful interventions, policy changes, and care practice improvements statewide or regionally.

27) What does CDC mean by "capacity building" in this opportunity?

Based on the NOFO description, capacity building refers to strengthening the ability of PQCs to design and execute QI initiatives more rapidly, support participating facilities effectively, measure results clearly, and integrate equity into planning, implementation, and evaluation.

28) How does Component B support equity across PQCs nationally?

Component B includes an explicit equity integration role. The awardee is expected to work with interested PQCs to embed a health equity perspective into QI design, implementation, measurement, and dissemination so improvements in perinatal outcomes are shared equitably.

29) What is the geographic scope of Component A compared with Component B?

Component A is focused on individual state or multi-state PQCs and their work across a state or multi-state region. Component B is national in scope, supporting PQCs across the United States through technical assistance, training, and capacity building.

30) What does "substantial involvement" from CDC typically mean for this cooperative agreement?

The NOFO characterizes the cooperative agreement structure as involving substantial CDC involvement through collaboration, guidance, and coordinated support, rather than CDC acting solely as a pass-through funder.

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