Opportunity Information: Apply for PAR 24 265
The NIH Shared Instrumentation Grant (SIG) Program (PAR-24-265) is a discretionary grant opportunity designed to help groups of NIH-supported investigators obtain access to major research equipment by funding the purchase or upgrade of a single, expensive, specialized, commercially available instrument or an integrated instrumentation system. The core purpose is to strengthen shared research infrastructure by placing high-end instrumentation into a shared-use environment, where multiple federally funded scientists can rely on the same platform rather than duplicating costly equipment across separate labs. This specific announcement is marked "S10 Clinical Trial Not Allowed," meaning the proposed project must not include a clinical trial component under NIH definitions.
Funding under this program is intended specifically for instrumentation costs, with an award floor of $50,000 and a maximum NIH award of $750,000. While there is no stated maximum purchase price for the instrument itself, the federal contribution through this mechanism cannot exceed $750,000, so applicants should plan accordingly if the total system price is higher (for example, by identifying institutional funds or other allowable sources to cover the difference, if applicable under NIH rules). The program supports a broad range of advanced, high-cost instruments commonly used across biomedical and health-related research, including (but not limited to) light microscopes, biomedical imaging systems, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, flow cytometers, DNA and protein sequencers, biosensors, and X-ray diffractometers. The emphasis is on equipment that is specialized and high-priced, where shared access materially improves the research capacity of a community of investigators.
Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (both those with and without 501(c)(3) status), as well as other organizations that meet NIH eligibility requirements. The opportunity explicitly recognizes a range of institution types among eligible applicants, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). At the same time, the eligibility rules are clear that non-U.S. entities are not allowed to apply: non-domestic (non-U.S.) organizations are ineligible, non-domestic components of U.S. organizations are ineligible, and foreign components (as defined by the NIH Grants Policy Statement) are not permitted under this announcement.
The sponsoring agency is the National Institutes of Health, and the funding activity aligns with health-related research infrastructure needs. The associated CFDA/assistance listing numbers include 93.242, 93.286, 93.351, 93.859, 93.866, 93.867. The opportunity was created on 2024-10-29, and the original closing date listed is 2027-06-01, indicating a multi-year window in which applications may be accepted according to the program’s submission schedule and NIH due dates.Apply for PAR 24 265
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242, 93.286, 93.351, 93.859, 93.866, 93.867.
- This funding opportunity was created on 2024-10-29.
- Applicants must submit their applications by 2027-06-01.
- Eligible applicants include: Public and State controlled institutions of higher education, Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, Others.
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NIH Shared Instrumentation Grant (SIG) Program (PAR-24-265) FAQs
What is the NIH Shared Instrumentation Grant (SIG) Program (PAR-24-265)?
The NIH Shared Instrumentation Grant (SIG) Program (PAR-24-265) is a discretionary NIH grant opportunity that helps groups of NIH-supported investigators gain access to major research equipment. It does this by funding the purchase or upgrade of a single, expensive, specialized, commercially available instrument or an integrated instrumentation system intended for shared use.
What is the main purpose of this funding opportunity?
The core purpose is to strengthen shared research infrastructure by placing high-end instrumentation into a shared-use environment. This supports multiple federally funded scientists using one platform instead of duplicating costly equipment across separate laboratories.
Is this grant intended for research projects or for equipment?
This program is intended specifically for instrumentation costs. The focus is on funding the purchase or upgrade of a single major piece of equipment (or an integrated system) rather than funding a research project.
What types of instruments are supported under this program?
The program supports a broad range of advanced, high-cost instruments used across biomedical and health-related research. Examples listed include light microscopes, biomedical imaging systems, mass spectrometers, nuclear magnetic resonance (NMR) spectrometers, flow cytometers, DNA and protein sequencers, biosensors, and X-ray diffractometers.
Does the instrument have to be commercially available?
Yes. The opportunity is described as supporting the purchase or upgrade of a single, expensive, specialized, commercially available instrument or an integrated instrumentation system.
What does "shared-use environment" mean in this announcement?
In this announcement, a shared-use environment means the instrument is placed in a setting where multiple federally funded investigators can access and rely on the same instrumentation platform, supporting a community of users rather than a single lab.
What is the minimum award amount?
The award floor is $50,000.
What is the maximum NIH award amount?
The maximum NIH award under this mechanism is $750,000.
Is there a maximum purchase price for the instrument?
No specific maximum purchase price for the instrument is stated. However, the NIH contribution through this program cannot exceed $750,000, so if the total system price is higher, applicants need to plan for how the difference would be covered (for example, through institutional funds or other allowable sources, if applicable under NIH rules).
Can the grant be used to purchase more than one instrument?
The opportunity is described as funding the purchase or upgrade of a single instrument or an integrated instrumentation system. Based on the information provided, it is not framed as a mechanism to buy multiple separate instruments.
Can the grant be used to upgrade an existing instrument instead of purchasing a new one?
Yes. The program explicitly supports either the purchase or the upgrade of a single, expensive, specialized instrument or an integrated instrumentation system.
Who is expected to benefit from the instrument?
The program is designed for groups of NIH-supported investigators and emphasizes shared access among multiple federally funded scientists who can rely on the same high-end equipment.
Are clinical trials allowed under this funding announcement?
No. The announcement is marked "S10 Clinical Trial Not Allowed," meaning the proposed project must not include a clinical trial component under NIH definitions.
What does "S10 Clinical Trial Not Allowed" mean for applicants?
It means the proposed project associated with the instrumentation request must not include a clinical trial component as defined by NIH. Applications should be structured to avoid proposing or including clinical trial activities.
Which organizations are eligible to apply?
Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (with or without 501(c)(3) status), as well as other organizations that meet NIH eligibility requirements.
Are minority-serving and tribal institutions eligible?
Yes. The opportunity explicitly recognizes eligible institution types including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).
Are non-U.S. (foreign) organizations eligible to apply?
No. Non-domestic (non-U.S.) organizations are ineligible to apply under this announcement.
Can a U.S. organization apply if the work involves a non-domestic component?
No. The eligibility rules stated indicate that non-domestic components of U.S. organizations are ineligible under this announcement.
Are foreign components permitted under this announcement?
No. Foreign components (as defined by the NIH Grants Policy Statement) are not permitted under this announcement.
Which federal agency sponsors this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What research area does this program support?
The funding activity aligns with health-related research infrastructure needs, with an emphasis on biomedical and health-related research that benefits from access to advanced shared instrumentation.
What are the associated CFDA/Assistance Listing numbers?
The associated CFDA/Assistance Listing numbers include 93.242, 93.286, 93.351, 93.859, 93.866, 93.867.
When was this opportunity created?
The opportunity was created on 2024-10-29.
What is the closing date for this opportunity?
The original closing date listed is 2027-06-01, indicating a multi-year window in which applications may be accepted according to the program's submission schedule and NIH due dates.
Does the listed closing date mean I can submit at any time until 2027-06-01?
The information provided indicates a multi-year window with applications accepted according to the program's submission schedule and NIH due dates. That suggests timing is still tied to NIH due dates rather than a single "submit any time" deadline.
What makes an instrument a good fit for this program?
Based on the description provided, a good fit is an instrument that is specialized and high-priced, commercially available, and would materially improve research capacity by serving multiple federally funded investigators through shared access.
Is the program limited to the example instruments listed?
No. The announcement states that supported instruments include, but are not limited to, the examples provided. This implies other advanced, high-cost instruments used in biomedical and health-related research may also be supported if they match the program purpose.
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