Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional) | PAR 24 110

Opportunity Information: Apply for PAR 24 110

The National Institutes of Health (NIH) is offering a discretionary research grant opportunity titled "Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)," funding opportunity number PAR-24-110. This initiative supports research projects that test and implement non-pharmacological interventions designed to improve sleep health, specifically in populations that experience health disparities. A central emphasis is not only on improving sleep itself, but also on studying sleep as a changeable (modifiable) factor that may help reduce disparities in other health outcomes, meaning applicants can propose work where better sleep is used as a pathway to improve broader health and reduce inequities.

The scientific focus is on intervention research rather than medication-based approaches. Proposed studies should aim to promote sleep health and reduce sleep health disparities using non-drug strategies, which could include behavioral, environmental, community, health system, technology-enabled, educational, or policy-related approaches, as long as they are non-pharmacological and grounded in a plausible pathway for improving sleep and related outcomes. Because the announcement is an R01 mechanism, it is oriented toward well-developed, hypothesis-driven or robust intervention-focused projects with clear aims, strong design, and meaningful potential for public health impact. The "Clinical Trials Optional" designation means applicants may propose studies that include a clinical trial if appropriate, but a clinical trial is not required; strong non-trial intervention research that still tests strategies to improve sleep and reduce disparities can also fit, depending on the specific design and NIH definitions.

Eligibility is broad and includes many types of domestic organizations and governmental units. Eligible applicants include state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; Native American tribal governments (federally recognized); public housing authorities and Indian housing authorities; Native American tribal organizations (other than federally recognized tribal governments); nonprofit organizations both with and without 501(c)(3) status (so long as they are not institutions of higher education in those categories); for-profit organizations other than small businesses; and small businesses. The opportunity also explicitly highlights additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), eligible federal agencies, faith-based or community-based organizations, regional organizations, Indian/Native American tribal governments other than federally recognized entities, and U.S. territories or possessions. This broad eligibility reflects an interest in encouraging applications from institutions and community-linked organizations that are closely connected to populations experiencing disparities and are well-positioned to carry out culturally responsive, context-aware intervention work.

At the same time, there are clear limits related to foreign participation. Non-domestic (non-U.S.) entities (foreign organizations) are not eligible to apply as applicant organizations, and non-domestic components of U.S. organizations are also not eligible to apply. However, foreign components, as defined in the NIH Grants Policy Statement, are allowed. In practical terms, that typically means a U.S.-based applicant organization can include a well-justified foreign component as part of the research (for example, a specific collaboration, site, or resource outside the U.S.), but the main applicant and eligible organizational structure must remain domestic and compliant with NIH policy requirements.

This funding opportunity is administered by NIH and is associated with multiple CFDA numbers (93.233, 93.273, 93.307, 93.361, 93.399, 93.837, 93.838, 93.839, 93.840, 93.853, 93.866), indicating that multiple NIH institutes, centers, or programs may participate or that the research areas intersect several NIH funding authorities. The posting shows an original closing date of 2027-09-07, suggesting the opportunity is intended to remain open over multiple receipt dates or cycles, consistent with many NIH program announcements. The listed award ceiling and expected awards fields are not specified in the provided source data, so applicants would typically need to consult the full NIH announcement text and related NIH policy guidance to understand budget expectations, project period norms, and any institute-specific considerations.

Overall, PAR-24-110 is designed to move beyond documenting sleep disparities and instead fund practical, testable solutions that improve sleep health in disparity-affected populations and clarify whether improving sleep can help narrow gaps in other health outcomes. Successful applications will generally align intervention design with the real-world contexts that shape sleep (home, neighborhood, work schedules, stress, healthcare access, environmental exposures, discrimination, and related social determinants), while also providing a rigorous plan to measure changes in sleep and downstream health or equity-relevant outcomes.

• The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.233, 93.273, 93.307, 93.361, 93.399, 93.837, 93.838, 93.839, 93.840, 93.853, 93.866.
• This funding opportunity was created on 2024-04-19.
• Applicants must submit their applications by 2027-09-07.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for PAR 24 110

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